pleio etymology

Etymology:

  • Greek: πλεῖον (pleîon), meaning "more, greater"

Meaning:

  • The expression or manifestation of multiple traits or characteristics in an organism that are controlled by a single gene or locus.

Origin:

The term "pleio" was first used in 1918 by the American geneticist Thomas Hunt Morgan to describe the phenomenon of multiple phenotypic effects resulting from a single gene mutation in the fruit fly, Drosophila melanogaster.

The concept of pleiotropy was further developed by other geneticists, including Richard Goldschmidt, who coined the term "pleiotropic gene" in 1938.

Pleiotropy is a common phenomenon in genetics and is observed in both eukaryotic and prokaryotic organisms. It can have important implications for the evolution of species and the genetic basis of complex traits.

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