Etymology:
Meaning:
A macule is a distinct, circumscribed, generally flat area of skin that is discolored compared to the surrounding skin. It can be caused by various factors, including:
Origin:
The term "macule" has been used in medical literature for centuries. It was first used in the 16th century by the French physician Ambroise Paré, who described it as a "small spot or mark on the skin." The term has since become widely accepted in dermatology and other medical fields.
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