amniocentesis etymology

Etymology

  • amni(on): Greek for "amnion," a membrane that surrounds the developing embryo
  • -centesis: Greek for "puncture"

Meaning

  • Surgical puncture of the amnion to obtain amniotic fluid for prenatal testing

Origin

Amniocentesis was first performed in 1854 by the German obstetrician Franz Naegele. The procedure was originally used to treat hydramnios (excessive amniotic fluid). In the 1950s, amniocentesis was adapted for prenatal diagnosis, specifically to detect genetic disorders such as Down syndrome.

Additional Notes

  • Amniocentesis is typically performed between 15-20 weeks of gestation.
  • The procedure carries a small risk of miscarriage (less than 1%).
  • Amniocentesis can also be used to determine the sex of the fetus, although this is not typically recommended as a primary reason for the procedure.
  • In recent years, non-invasive prenatal testing (such as NIPT) has become increasingly common as a first-line screening for genetic disorders. However, amniocentesis remains the gold standard for prenatal diagnosis due to its high accuracy.

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